Painkiller Jane was created by Jimmy Palmiotti and Joe Quesada for Event Comics in 1995. Originally a five-issue mini-series, the character went on to star in numerous crossover titles with the likes of the Punisher, Vampirella, and Hellboy.
After Event comics, the character was exclusively written by Jimmy Palmiotti and drawn by various artists as it jumped from publisher to publisher. The series relaunched at Dynamite Entertainment with the first mini-series selling out. After that Icon- an independent label for creator owned work at Marvel comics, published two mini-series. The character then came back to PaperFilms, a company owned by Jimmy Palmiotti and Amanda Conner where it is currently published. Painkiller Jane has been published all over the world in at least 8 languages to date. The comics have been the basis for a film and television series and is currently in development with Jessica Chastain.
EHT Comics 