In the last major storyline of the first X-Factor series, published in early 1991, Apocalypse kidnaps Nathan Summers, sensing that he would grow up to be a powerful mutant and possible threat. X-Factor rescue Nathan from Apocalypse’s lunar base, but find him infected with a “techno-organic” virus that cannot be treated. A clan of rebels from the future, known as the Askani, send a representative to the present time to bring Nathan 2,000 years into the future to be treated. Fully grown, he returns to the 20th century as the antihero, Cable.
X-Factor, the X-Men, and several minor characters team up to fight the telepathic Shadow King in another crossover event, The Muir Island Saga. Afterward, the original members of X-Factor rejoin the X-Men and several characters from various X-Men-related series become founding members of a new X-Factor.
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