In 1998, Daredevil‘s numbering was rebooted, with the title “canceled” with issue #380 and revived a month later as part of the Marvel Knights imprint. Joe Quesada drew the new series, written by filmmaker Kevin Smith. Its first story arc, “Guardian Devil“, depicts Daredevil struggling to protect a child whom he is told could either be the Messiah or the Anti-Christ. Murdock experiences a crisis of faith exacerbated by the discovery that Karen Page has AIDS (later revealed to be a hoax) and her subsequent death at Bullseye‘s hands. When he discovers that the true party responsible for the scheme is Mysterio, who is currently dying of cancer, he leaves Mysterio to commit suicide, deciding to use the money Karen left him in her will to re-open Nelson & Murdock.
Smith was succeeded by writer-artist David Mack, who contributed the seven-issue “Parts of a Hole” (vol. 2, #9–15). The arc introduced Maya Lopez, also known as Echo, a deaf martial artist.
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